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![Anti-Caspase-11, clone 6D225](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2088-56D.100 | 100 µg | - | - |
3 - 19 business days* |
715.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Caspase-11, (also known as CASP-11, ICH-3, ICE-B) promotes IL-b processing by procaspase-1 (ICE)... more
Product information "Anti-Caspase-11, clone 6D225"
Caspase-11, (also known as CASP-11, ICH-3, ICE-B) promotes IL-b processing by procaspase-1 (ICE) and therefore may also have a role in inflammatory response as evident by a 30 fold increase in CASP-11 activity by LPS. The mouse and rat CASP-11 (373aa) are most homologous to human CASP-4 (377aa) protein (ICErel-II, TX, ICH-2) and could possibly be the ortholog of human CASP-4. The pro-or zymogen form of CASP-11 is activated by Granzyme-B or cathepsin-B and the processed enzyme consists of two large p20 (20kD) and two small ~p10 (10kDa subunits. CASP-11 is highly expressed in lung and spleen, weaker in heart and very little in liver, kidney, testis and skeletal muscle but has not been detected in the brain. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: detects two bands of ~38kD and ~43kD., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Ich3, Anti-Casp4, Anti-Caspl, Anti-CASP-4, Anti-Casp11, EC=3.4.22.64, Anti-CASP-11, Anti-Caspase-4, Anti-Caspase-11, Anti-Protease ICH-3, Anti-Caspase-4 subunit p20 |
Supplier: | United States Biological |
Supplier-Nr: | C2088-56D |
Properties
Application: | FC, WB |
Antibody Type: | Monoclonal |
Clone: | 6D225 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | mouse, rat |
Immunogen: | p20 fragment of mouse caspase-11. |
Database Information
KEGG ID : | K04394 | Matching products |
UniProt ID : | P70343 | Matching products |
Gene ID | GeneID 12363 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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