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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1088-20 | 20 µg | - |
3 - 11 business days* |
373.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family.... more
Product information "Anti-Carcinoembryonic Antigen (CEA) / CD66 Recombinant Mouse Monoclonal Antibody (clone:rC66/1009)"
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression, induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). [The UniProt Consortium]
Keywords: | Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-Carcinoembryonic antigen-related cell adhesion molecule 5, Anti-Carcinoembryonic Antigen (CEA) / CD66 Recombinant Mouse Monoclonal Antibody (Clone:rC66/1009 |
Supplier: | Abeomics |
Supplier-Nr: | 12-1088-20 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | rC66/1009 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant full-length human CD66e protein |
Format: | Purified |
Database Information
KEGG ID : | K06499 | Matching products |
UniProt ID : | P06731 | Matching products |
Gene ID | GeneID 1048 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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