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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA026304.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-HPA026304.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Key microtubule-organizing protein that specifically binds the minus-end of... more
Product information "Anti-CAMSAP2"
Protein function: Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubule minus- ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In addition, it also reduces the velocity of microtubule polymerization (PubMed:24486153, PubMed:24706919). Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes (PubMed:27666745). Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi- associated proteins AKAP9 and PDE4DIP, required to tether non- centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745). Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation (PubMed:24908486). Through the microtubule cytoskeleton, regulates the autophagosome transport (PubMed:28726242). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 77%
Keywords: | Anti-Calmodulin-regulated spectrin-associated protein 2, Anti-Calmodulin-regulated spectrin-associated protein 1-like protein 1 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA026304 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SSVHGVSFDI SFDKEDSVQR STPNRGITRS ISNEGLTLNN SHVSKHIRKN LSFKPINGEE EAESIEEELN IDSHSDLKSC VPL (ATA-APrEST76668) |
Database Information
KEGG ID : | K17493 | Matching products |
UniProt ID : | Q08AD1 | Matching products |
Gene ID : | GeneID 23271 | Matching products |
Protein Atlas Nr. : | ENSG00000118200 |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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