Anti-CACNA1C, clone S57

Anti-CACNA1C, clone S57
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG24118.50 50 µg - -

6 - 14 business days*

536.00€
 
Protein function: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives... more
Product information "Anti-CACNA1C, clone S57"
Protein function: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:2474130, PubMed:2169433, PubMed:8232554, PubMed:9502794, PubMed:9278523, PubMed:15615847, PubMed:17525370, PubMed:21127204, PubMed:22928916, PubMed:23145875, PubMed:29363593, PubMed:22649239). Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm (PubMed:23145875). Plays an important role in excitation-contraction coupling in the heart (PubMed:17525370, PubMed:22928916, PubMed:23145875). Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group (Probable). [The UniProt Consortium]
Keywords: Anti-CACH2, Anti-CACNA1C, Anti-CACB-receptor, Anti-Smooth muscle calcium channel blocker receptor, Anti-Voltage-gated calcium channel subunit alpha Cav1.2, Anti-Voltage-dependent L-type calcium channel subunit alpha-1C, Anti-Calcium channel, L type
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG24118

Properties

Application: ICC, IF, IHC (paraffin), IP, WB
Antibody Type: Monoclonal
Clone: S57
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, hamster, rabbit
Immunogen: Rabbit fusion protein of CACNA1C a.a 1507-1733
MW: 249 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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