Anti-BTLA (icatolimab biosimilar)mAb

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
DIM-BME100054.50	50 µg		-	-	7 - 16 business days*		115.00€
DIM-BME100054.100	100 µg		-	-	7 - 16 business days*		227.00€

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Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor... more

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Product information "Anti-BTLA (icatolimab biosimilar)mAb"

Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044). [The UniProt Consortium]

Keywords:	Anti-BTLA, Anti-CD272, Anti-BTLA (icatolimab biosimilar)mAb
Supplier:	DIMA
Supplier-Nr:	BME100054

Properties

Antibody Type:	Monoclonal
Conjugate:	No
Host:	Chimeric
Species reactivity:	human
Format:	Lyophilized

Database Information

CAS :	12\| Matching products
UniProt ID :	Q7Z6A9 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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