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![Anti-BMPR1B](https://www.biomol.com/media/image/8f/7d/0f/NSJ-F41873-0-08ML_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F41873-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F41873-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a member of the bone morphogenetic... more
Product information "Anti-BMPR1B"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Protein function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. [The UniProt Consortium]
Keywords: | Anti-BMPR1B, Anti-CDw293, Anti-BMPR-1B, EC=2.7.11.30, Anti-BMP type-1B receptor, Anti-Bone morphogenetic protein receptor type-1B, BMPR1B Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F41873 |
Properties
Application: | WB, IHC, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 134-162 from the human protein was used as the immunogen for this BMPR1B antibody. |
Format: | Purified |
Database Information
KEGG ID : | K13578 | Matching products |
UniProt ID : | O00238 | Matching products |
Gene ID | GeneID 658 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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