Anti-BMI1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-25210	100 µl		-	-	3 - 15 business days*		742.00€

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BMI1 (UniProtKB/Swiss Prot entry P35226) is a component of a Polycomb group (PcG) multiprotein... more

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Product information "Anti-BMI1"

BMI1 (UniProtKB/Swiss Prot entry P35226) is a component of a Polycomb group (PcG) multiprotein PRC1 like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. BMI1 is required to stimulate the E3 ubiquitin protein ligase activity of RNF2/RING2 in the PRC1 complex.

Keywords:	Anti-BMI1, Anti-PCGF4, Anti-RING finger protein 51, Anti-Polycomb complex protein BMI-1, Anti-Polycomb group RING finger protein 4
Supplier:	BPS Bioscience
Supplier-Nr:	25210

Properties

Application:	ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	mouse BMI1 (BMI1 polycomb ring finger oncogene) using two KLHconjugated synthetic peptides containing a sequence from the central and the C terminal region of the protein, respectively.
Format:	Gene Regulation