Anti-Beta-2 Microglobulin, clone C21.48A1

Anti-Beta-2 Microglobulin, clone C21.48A1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2803SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. The antibody recognizes the hidden... more
Product information "Anti-Beta-2 Microglobulin, clone C21.48A1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. The antibody recognizes the hidden determinant of beta-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain). Beta-2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta-2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta-2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy). Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [The UniProt Consortium]
Keywords: Anti-B2M, Anti-CDABP0092, Beta-2 Microglobulin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2803SAF

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: C21.48A1
Conjugate: No
Host: Mouse
Species reactivity: human, primates
Immunogen: Soluble beta 2 microglobulin
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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