Anti-Beta-2 Microglobulin, clone BBM.1

Anti-Beta-2 Microglobulin, clone BBM.1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2802SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 12kDa, identified as... more
Product information "Anti-Beta-2 Microglobulin, clone BBM.1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 12kDa, identified as microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha- heavy chain that contains three subdomains (alpha-1, alpha-2, alpha-3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha-3 subdomain of the alpha- heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha-1 and alpha-2 domains of the alpha- heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes. Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [The UniProt Consortium]
Keywords: Anti-B2M, Anti-CDABP0092, Beta-2 Microglobulin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2802SAF

Properties

Application: FC, IF, IF, IP
Antibody Type: Monoclonal
Clone: BBM.1
Conjugate: No
Host: Mouse
Species reactivity: human, primates
Immunogen: MOLT-4 cell line
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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