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![Anti-BARD1, NT (BARD1, BRCA1-associated RING domain protein 1) (Azide free) (APC)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
032422-APC.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
BARD1 is a protein which interacts with the N-terminal region of BRCA1. In addition to its... more
Product information "Anti-BARD1, NT (BARD1, BRCA1-associated RING domain protein 1) (Azide free) (APC)"
BARD1 is a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-BARD1, Anti-BARD-1, EC=6.3.2.-, Anti-BRCA1-associated RING domain protein 1 |
Supplier: | United States Biological |
Supplier-Nr: | 032422-APC |
Properties
Application: | FLISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | APC |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | BARD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-135 amino acids from the N-terminal region of human BARD1. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10683 | Matching products |
UniProt ID : | Q99728 | Matching products |
Gene ID | GeneID 580 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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