Anti-ATP6V0D1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA016938.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA016938.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Subunit of the integral membrane V0 complex of the lysosomal... more

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Product information "Anti-ATP6V0D1"

Protein function: Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase) (PubMed:28296633, PubMed:30374053). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (PubMed:30374053). May play a role in coupling of proton transport and ATP hydrolysis. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-p39, Anti-ATP6D, Anti-V-ATPase subunit d 1, Anti-V-ATPase AC39 subunit, Anti-32 kDa accessory protein, Anti-V-type proton ATPase subunit d 1, Anti-Vacuolar proton pump subunit d 1, Anti-V-ATPase 40 kDa accessory protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA016938

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TELSKEDRAK LFPHCGRLYP EGLAQLARAD DYEQVKNVAD YYPEYKLLFE GAGSNPGDKT LEDRFFEHEV KLNKLAFLNQ FHFGVFYAFV KL (ATA-APrEST71568)