Anti-ATG4C

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-Y84	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-ATG4C antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-ATG4C"

Anti-ATG4C antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins. Protein function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. [The UniProt Consortium]

Keywords:	Anti-APG4C, Anti-ATG4C, EC=3.4.22.-, Anti-Autophagin-3, Anti-Cysteine protease ATG4C, Anti-AUT-like 3 cysteine endopeptidase, Anti-Autophagy-related protein 4 homolog C, Anti-Autophagy-related cysteine endopeptidase 3
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-Y84

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	18 amino acid peptide near the C-terminus of human ATG4C
Format:	Purified