Anti-Atg4B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-897A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-897A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and... more

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Product information "Anti-Atg4B"

Protein function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. [The UniProt Consortium]

Keywords:	Anti-ATG4B, Anti-APG4B, Anti-hAPG4B, EC=3.4.22.-, Anti-Autophagin-1, Anti-Cysteine protease ATG4B, Anti-AUT-like 1 cysteine endopeptidase, Anti-Autophagy-related protein 4 homolog B, Anti-Autophagy-related cysteine endopeptidase 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-897A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, gorilla, chimpanzee, white-tufted-ear marmoset, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-897A-T maps to a region between residue 275 and 325 of human Autophagy-related Protein 4 Homolog B using the numbering given in entry NP_037457.3 (GeneID 23192).
Format:	Antigen Affinity Purified