Anti-ATG4B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-Y83	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-ATG4B antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-ATG4B"

Anti-ATG4B antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ATG4B antibody is human, mouse and rat reactive. At least two isoforms of ATG4B are known to exist, this antibody will detect only the larger isoform. ATG4B is predicted to not cross-react with other ATG4 proteins. Protein function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. [The UniProt Consortium]

Keywords:	Anti-APG4B, Anti-ATG4B, Anti-hAPG4B, EC=3.4.22.-, Anti-Autophagin-1, Anti-Cysteine protease ATG4B, Anti-AUT-like 1 cysteine endopeptidase, Anti-Autophagy-related protein 4 homolog B, Anti-Autophagy-related cysteine endopeptidase 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-Y83

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	17 amino acid peptide near the C-terminus of human ATG4B.
Format:	Purified