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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A3619-81.100 | 100 µg | - | - |
3 - 19 business days* |
897.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Achaete Scute homolog 2 (also known as mammalian aschaete-scute homolog 2 or Mash2) is a nuclear... more
Product information "Anti-ASCL2 (Achaete-scute complex homolog 2 (Drosophila), Achaete-scute homolog 2, ASH2, ASH-2, bHLH"
Achaete Scute homolog 2 (also known as mammalian aschaete-scute homolog 2 or Mash2) is a nuclear protein expressed specifically in the extravillous trophoblasts of developing placenta. Placental development involves control by the basic helix-loop-helix transcription factor Achaete Scute homolog 2, which may regulate HIF (hypoxia) in the formation of spongiotrophoblasts. Targeted mutagenesis of Achaete Scute homolog 2 yielded loss of function results in embryonic lethality at midgestation due to placental failure associated with a lack of spongiotrophoblasts and reduced labyrinthine trophoblast layers. In addition to healthy placental development, Achaete Scute proteins may also be involved in the determination of neuronal precursors in the central and peripheral nervous systems. Achaete Scute homolog 2 has also been implicated as a controller of intestinal stem cell fate and is essential for the maintenance of adult intestinal stem cells. Applications: Suitable for use in Western Blot, Immunoprecipitation (ChIP) and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/mL detected ASCL2 in 10ug of human placenta tissue lysate., Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, I1904-06H: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Achaete-scute homolog 2, Anti-Class A basic helix-loop-helix protein 45 |
Supplier: | United States Biological |
Supplier-Nr: | A3619-81 |
Properties
Application: | ICC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 10F628 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant protein corresponding to C-terminus of human Achaete Scute homolog 2 (His). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K09067 | Matching products |
UniProt ID : | Q99929 | Matching products |
Gene ID : | GeneID 430 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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