Anti-ARPC3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA006550.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA006550.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin... more
Product information "Anti-ARPC3"
Protein function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%
Keywords: Anti-ARC21, Anti-ARPC3, Anti-p21-ARC, Anti-Arp2/3 complex 21 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 3
Supplier: Atlas Antibodies
Supplier-Nr: HPA006550

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DPDTKLIGNM ALLPIRSQFK GPAPRETKDT DIVDEAIYYF KANVFFKNYE IKNEADRTLI YITLYISECL KKLQKCNSKS QGEKEMYTLG ITNFPIPGEP GFPLNAIYAK PANKQEDEVM RAYLQQLRQE TGLRLCEKVF DPQNDKPSK (ATA-APrEST70107)

Database Information

KEGG ID : K05756 | Matching products
UniProt ID : O15145 | Matching products
Gene ID : GeneID 10094 | Matching products
Protein Atlas Nr. : ENSG00000111229

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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