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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA008352.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA008352.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Actin-binding component of the Arp2/3 complex, a multiprotein complex that... more
Product information "Anti-ARPC2"
Protein function: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%
| Keywords: | Anti-ARC34, Anti-ARPC2, Anti-PRO2446, Anti-p34-ARC, Anti-Arp2/3 complex 34 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 2 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA008352 |
Properties
| Application: | IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TVVFSTVFKD DDDVVIGKVF MQEFKEGRRA SHTAPQVLFS HREPPLELKD TDAAVGDNIG YITFVLFPRH TNASARDNTI NLIHTFRDYL HYHIKCSKAY IHTRMRAKTS DFLKVLNRAR PDAEKKEMKT ITGKTFSSR (ATA-APrEST71119) |
Database Information
| KEGG ID : | K05758 | Matching products |
| UniProt ID : | O15144 | Matching products |
| Gene ID : | GeneID 10109 | Matching products |
| Protein Atlas Nr. : | ENSG00000163466 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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