Anti-ARP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55160.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: ATP-binding component of the Arp2/3 complex, a multiprotein complex that... more

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Product information "Anti-ARP2"

Protein function: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076). Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double- strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium]

Keywords:	Anti-ARP2, Anti-ACTR2, Anti-Actin-like protein 2, Anti-Actin-related protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55160

Properties

Application:	FC, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat, bovine, chicken, Xenopus)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 191-219 (Center) of Human ARP2
Format:	Ammonium Sulfate Precipitated