Anti-APLNR / APJ

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40385.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN)... more

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Product information "Anti-APLNR / APJ"

Protein function: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753, PubMed:28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)- derived endothelial cells migration into the developing heart to promote coronary blood vessel development. Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed:25639753, PubMed:28137936). [The UniProt Consortium]

Keywords:	Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ, Anti-G-protein coupled receptor HG11
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40385

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	KLH-conjugated synthetic peptide within the center region of Human APJ
MW:	42 kD
Format:	Antigen Affinity Purified