Anti-Angiotensin(1-7) Mas Receptor

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-EA176.100 100 µl - -

10 - 14 business days*

283.00€
 
The angiotensin-(1-7) Mas receptor is the recently identified receptor of the biologically active... more
Product information "Anti-Angiotensin(1-7) Mas Receptor"
The angiotensin-(1-7) Mas receptor is the recently identified receptor of the biologically active heptapeptide angiotensin-(1-7).Angiotensin (Ang)-(1-7) is a metabolite of the well known peptide hormone Angiotensin (Ang) II, a key component of the renin-angiotensin system (RAS) that has a central role in cardiovascular homeostasis. Protein function: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. [The UniProt Consortium] Recommended dilutions: WB 1:2,000-5,000   IHC 1:200-500. Cellular localization: Cell membrane, Membrane
Keywords: Anti-MAS, Anti-MAS1, Anti-Proto-oncogene Mas, Angiotensin(1-7) Mas Receptor Rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: EA176

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic Peptide
MW: 36-50 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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