Anti-alpha-2-MACROGLOBULIN

Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-101-207-0100 100 µg - -

6 - 10 business days*

684.00€
 
Anti-alpha-2-MACROGLOBULIN is an IgG fraction antibody purified from monospecific antiserum by a... more
Product information "Anti-alpha-2-MACROGLOBULIN"
Anti-alpha-2-MACROGLOBULIN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified a2-Macroglobulin [Human Plasma].  Cross reactivity against a2-Macroglobulin from other sources is unknown. Protein function: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. [The UniProt Consortium]
Keywords: Anti-A2M, Anti-CPAMD5, Anti-FWP007, Anti-Alpha-2-M, Anti-Alpha-2-macroglobulin, Anti-C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-101-207-0100

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: a2-Macroglobulin [Human Plasma]
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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