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![Anti-ALIX](https://www.biomol.com/media/image/06/d6/1f/A302-938A-T_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-938A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-938A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Class E VPS protein involved in concentration and sorting of cargo proteins of... more
Product information "Anti-ALIX"
Protein function: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release, this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation. Regulates exosome biogenesis in concert with SDC1/4 and SDCBP (PubMed:22660413). [The UniProt Consortium]
Keywords: | Anti-Hp95, Anti-AIP1, Anti-PDCD6IP, Anti-PDCD6-interacting protein, Anti-ALG-2-interacting protein 1, Anti-ALG-2-interacting protein X, Anti-Programmed cell death 6-interacting protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-938A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse, rat) |
Immunogen: | synthetic peptide. The epitope recognized by A302-938A-T maps to a region between residue 818 and 868 of human Apoptosis-Linked Gene 2-Interacting Protein X using the numbering given in entry NP_037506.2 (GeneID 10015). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12200 | Matching products |
UniProt ID : | Q8WUM4 | Matching products |
Gene ID | GeneID 10015 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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