Anti-ALDH2

Anti-ALDH2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31184 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Aldehyde Dehydrogenase 2 is a human gene.... more
Product information "Anti-ALDH2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Aldehyde Dehydrogenase 2 is a human gene. The enzyme encoded by this gene belongs to the ALDH family of enzymes that catalyze the chemical transformation from acetaldehyde to acetic acid. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Hsu et al.(1985) assigned the ALDH2 locus to chromosome 12 by means of a cDNA probe and Southern blot analysis of somatic cell hybrids. Using an unbiased proteomic search, Chen et al.(2008) identified mitochondrial ALDH2 as an enzyme whose activation correlated with reduced ischemic heart damage in rodent models. A high-throughput screen identified a small molecule activator of ALDH2, which they called Alda-1, that, when administered to rats before an ischemic event, reduced infarct size by 60%, most likely through its inhibitory effect on the formation of cytotoxic aldehydes.
Keywords: Anti-ALDM, Anti-ALDH2, Anti-ALDHI, Anti-ALDH-E2, EC=1.2.1.3, Anti-ALDH class 2, Anti-Aldehyde dehydrogenase, mitochondrial, ALDH2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31184

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Immunogen: An amino acid sequence from the N-terminus of human Aldehyde Dehydrogenase 2 (SAAATQAVPAPNQQPE) was used as the immunogen for this ALDH2 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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