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Product information "Anti-ALDH1A1/ALDH1A2/ALDH1A3"
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. Protein function: Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal. May have a broader specificity and oxidize other aldehydes in vivo (PubMed:19296407, PubMed:26373694, PubMed:25450233). [The UniProt Consortium]
Keywords:
Anti-ALHDII, Anti-RalDH1, Anti-RALDH 1, Anti-ALDH-E1, Anti-Retinal dehydrogenase 1, Anti-Aldehyde dehydrogenase, cytosolic, Anti-Aldehyde dehydrogenase family 1 member A1, ALDH1A1/ALDH1A2/ALDH1A3 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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