Anti-AF/LE Purified Anti-Mouse CD106, clone M/K-2.7

Item number	Size	Manual	Delivery time	Price
E-AB-F10910.25	25 mg	-	7 - 16 business days*	22.00€
E-AB-F10910.100	100 mg	-	7 - 16 business days*	55.00€
E-AB-F10910.1	1 mg	-	7 - 16 business days*	158.00€
E-AB-F10910.5	5 mg	-	7 - 16 business days*	629.00€
E-AB-F10910.50	50 mg	-	7 - 16 business days*	3,145.00€

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CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as... more

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Product information "Anti-AF/LE Purified Anti-Mouse CD106, clone M/K-2.7"

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (alpha4/beta1 integrin) and LPAM-1 (alpha4/beta7 integrin). Protein function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [The UniProt Consortium]

Keywords:	Anti-Vcam1, Anti-CD106, Anti-Vcam-1, Anti-VCAM-1, Anti-V-CAM 1, Anti-Vascular cell adhesion protein 1, AF/LE Purified Anti-Mouse CD106 Monoclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-F10910