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![Anti-ADA/Adenosine Deaminase](https://www.biomol.com/media/image/ec/a2/69/A305-182A-T_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A305-182A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A305-182A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine... more
Product information "Anti-ADA/Adenosine Deaminase"
Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4 (PubMed:20959412). Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion (PubMed:11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. Enhances CD4+ T-cell differentiation and proliferation (PubMed:20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (PubMed:23193172). Stimulates plasminogen activation (PubMed:15016824). Plays a role in male fertility (PubMed:21919946, PubMed:26166670). Plays a protective role in early postimplantation embryonic development. [The UniProt Consortium]
Keywords: | Anti-ADA, Anti-ADA1, Anti-Adenosine deaminase, Anti-Adenosine aminohydrolase |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A305-182A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic peptide. The epitope recognized by A305-182A-T maps to a region between residue 1 to 50 of human Adenosine deaminase using the numbering given in entry P00813.3 (GeneID 100). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K01488 | Matching products |
UniProt ID : | P00813 | Matching products |
Gene ID | GeneID 100 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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