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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES18494.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES18494.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric... more
Product information "Anti-ACHA2"
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009], Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.
Keywords: | Anti-CHRNA2, Anti-Neuronal acetylcholine receptor subunit alpha-2, ACHA2 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES18494 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized peptide derived from human ACHA2 AA range: 219-269 |
Format: | Purified |
Database Information
KEGG ID : | K04804 | Matching products |
UniProt ID : | Q15822 | Matching products |
Gene ID : | GeneID 1135 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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