Anti-ACE2 (human) (Clone AC384)

Anti-ACE2 (human) (Clone AC384)
COVID-19 Research
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay30584-50 50 µg -

6 - 10 business days*

360.00€
Cay30584-100 100 µg -

6 - 10 business days*

537.00€
 
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded... more
Product information "Anti-ACE2 (human) (Clone AC384)"
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded by ACE2 in humans. It is a type I transmembrane protein composed of a cytoplasmic tail and an extracellular domain containing an HEMGH motif, characteristic of zinc-metallopeptidases, which exhibits carboxymonopeptidase activity. ACE2 is expressed in vascular endothelial cells where it catalyzes the conversion of angiotensin II to the vasodilatory peptide angiotensin 1-7 to regulate systemic blood pressure and angiotensin I to angiotensin 1-9, a peptide that counter-regulates the function of angiotensin II. It is also expressed in the epithelial cells of the kidney, heart, lung, small intestine, and liver and has roles in fluid homeostasis, cardiac contractility, and amino acid absorption, as well as the prevention of pulmonary fibrosis and hypertension. ACE2 also acts as a functional receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 to facilitate viral entry into host cells. Cayman's ACE2 (human) Monoclonal Antibody (Clone AC384) can be used for ELISA and Western blot (WB) applications.Synonyms: ACE-related Carboxypeptidase, ACEH, Angiotensin-converting Enzyme 2, Angiotensin-converting Enzyme Homolog, Metalloprotease MPROT15. Immunogen: Recombinant human ACE2. Clone Designation: AC384. Formulation: (Request formulation change), 50 or 100 µg of Protein G-purified monoclonal antibody. Storage Buffer: 0.2 µm-filtered solution in PBS, pH 7.4. Host: Mouse. Isotype: IgG1kappa. Applications: ELISA and WB.
Keywords: ACEH, ACE-related Carboxypeptidase, Angiotensin-converting Enzyme Homolog, Metalloprotease MPROT15
Supplier: Cayman Chemical
Supplier-Nr: 30584

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: AC384
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human ACE2
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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Anti-ACE2 Anti-ACE2
From 134.00€ *
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