Anti-ABCB5, clone CL12512

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-AMAb91793.25	25 µl				7 - 10 business days*		320.00€
ATA-AMAb91793.100	100 µl				7 - 10 business days*		450.00€

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Monoclonal Antibody against Human TMPRSS2, Clone ID: CL12512, Gene description: Transmembrane... more

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Product information "Anti-ABCB5, clone CL12512"

Monoclonal Antibody against Human TMPRSS2, Clone ID: CL12512, Gene description: Transmembrane serine protease 2, Alternative Gene Names: PRSS10, Validated applications: IHC, Uniprot ID: O15393, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate (PubMed:25122198). Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells (PubMed:15537383, PubMed:26018085, PubMed:25122198). In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia. [The UniProt Consortium] Mouse gene identity: 66% Rat gene identity: 66%

Keywords:	Anti-PRSS10, EC=3.4.21.-
Supplier:	Atlas Antibodies
Supplier-Nr:	AMAb91793

Properties

Application:	IHC
Antibody Type:	Monoclonal
Clone:	CL12512
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (ATA-APrEST87138)
Format:	Purified