Anti-15 Lipoxygenase 2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG58231.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific... more

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Product information "Anti-15 Lipoxygenase 2"

Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)- HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells. [The UniProt Consortium]

Keywords:	Anti-ALOX15B, Anti-15-LOX-2, Anti-15-LOX-B, EC=1.13.11.-, EC=1.13.11.33, Anti-15-lipoxygenase 2, Anti-Arachidonate 15-lipoxygenase B, Anti-Linoleate 13-lipoxygenase 15-LOb, Anti-Arachidonate 15-lipoxygenase type II
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG58231

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Recombinant funsion protein corresponding to aa. 1-200 of Human 15 Lipoxygenase 2 (NP_001132.2)
MW:	75 kD
Format:	Affinity Purified