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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG55210.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific... more
Product information "Anti-12 Lipoxygenase"
Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)- hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation. [The UniProt Consortium]
Keywords: | Anti-12LO, Anti-ALOX12, Anti-12S-LOX, EC=3.3.2.-, EC=1.13.11.31, Anti-12S-lipoxygenase, Anti-Lipoxin synthase 12-LO, Anti-Platelet-type lipoxygenase 12, Anti-Arachidonate 12-lipoxygenase, 12S-type |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG55210 |
Properties
Application: | FC, ICC, IF, IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | KLH-conjugated synthetic peptide corresponding to aa. 618-650 (C-terminus) of Human 12 Lipoxygenase |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K00458 | Matching products |
UniProt ID : | P18054 | Matching products |
Gene ID | GeneID 239 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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