Tedizolid phosphate is a prodrug form of tedizolid, an antibiotic with activity against Gram-positive bacteria. Tedizolid phosphate is rapidly converted by non-specific phosphatases to tedizolid, which inhibits the growth of S. aureus, S. epidermidis, E. faecalis, E. faecium, S. pneumoniae, and S. pyogenes (MICs =...

Linezolid is a synthetic oxazolidinone antibiotic with activity against a wide range of Gram-positive bacteria, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), penicillin-resistant pneumococci, vancomycin-resistant enterococci, various anaerobic bacteria, and several...

Cadazolid is an oxazolidinone-type antibiotic that has activity against a panel of C. difficile strains, including those resistant to fluoroquinolones and linezolid (Cay-15012, MICs = 0.125-0.5 µg/ml). It inhibits toxin A and B formation in stationary-phase cultures and spore formation in late exponential cultures...

Delpazolid is an oxazolidinone antibiotic. It is active against a wide range of Gram-positive bacterial clinical isolates, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), and penicillin-resistant S....

PNU 100480 is an oxazolidinone antibiotic that is active against multidrug resistant tuberculosis. It inhibits the growth of M. tuberculosis replicating and nonreplicating strains (MIC = ~400 ng/ml for both) and of clinical isolates that are susceptible or resistant to a combination of isoniazid (Cay-20378),...

Radezolid is an oxazolidinone antibiotic and a derivative of linezolid (Cay-15012). It is active against a variety of bacterial clinical isolates, including strains of methicillin-sensitive and -resistant S. aureus, vancomycin-sensitive and -resistant E. faecalis and E. faecium, and linezolid-resistant S. aureus, S....

Tedizolid is an oxazolidinone antibiotic and active metabolite of the antibiotic tedizolid phosphate (Cay-23729). Tedizolid phosphate is converted to tedizolid by phosphatases in vivo. It is active against a wide variety of clinical isolates, including isolates of methicillin-resistant S. aureus (MRSA), E. faecalis,...

Tedizolid-13C-d3 is intended for use as an internal standard for the quantification of tedizolid (Cay-32952) by GC- or LC-MS. Tedizolid is an oxazolidinone antibiotic and active metabolite of the antibiotic tedizolid phosphate (Cay-23729). Tedizolid phosphate is converted to tedizolid by phosphatases in vivo. It is...