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ML115
Item number: TGM-T35544-100mg
Description: ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFkappaB anti-targets. Target: STAT. Smiles: COc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl. References: Madoux F, et al. Modulators of STAT Transcription Factors for the...
| Application: | Cell-permeable STAT3 activator |
| CAS | 912798-42-6 |
| MW: | 322.74 D |
From 94.00€
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ML-115
Item number: Cay15178-1
Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. ML-115 is an isoxazole carboxamide that acts as a cell-permeable STAT3 activator (EC50 = 2 nM) and is more than 28,000-fold selective for STAT3 over STAT1 and NF-kappaB. It...
| Keywords: | CID 6619100, SID 14735210, N-(4-chloro-2,5-dimethoxyphenyl)-5-cyclopropyl-3-isoxazolecarboxamide |
| Application: | Cell-permeable STAT3 activator |
| CAS | 912798-42-6 |
| MW: | 322.7 D |
From 66.00€
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