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PF-573228
Item number: TGM-T2001-100mg
Description: PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM. Target: FAK, Apoptosis. Smiles: CS(=O)(=O)c1cccc(CNc2nc(Nc3ccc4NC(=O)CCc4c3)ncc2C(F)(F)F)c1. References: Slack-Davis JK, et al. J Biol Chem, 2007, 282(20), 14845-14852.
| Keywords: | PF 573228 |
| CAS | 869288-64-2 |
| MW: | 491.49 D |
From 45.00€
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PF-573228
Item number: Cay14924-1
Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are overexpressed in many types of cancer. PF-573228 inhibits FAK with IC50 values of 4 and 30-100 nM for a purified...
| Keywords: | FAK Inhibitor II, Focal Adhesion Kinase Inhibitor II,... |
| Application: | PTK2 inhibitor |
| CAS | 869288-64-2 |
| MW: | 491.5 D |
From 43.00€
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