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4-Hydroxytamoxifen
4-Hydroxytamoxifen

Item number: TGM-T4420-100mg

Description: 4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer research. Target: Estrogen/progestogen Receptor, Estrogen Receptor/ERR. Smiles:...
Keywords: (Z)-4-hydroxy Tamoxifen, ICI 79280, trans-4-Hydroxytamoxifen
Application: Tamoxifen metabolite
CAS 68047-06-3
MW: 387.51 D
From 53.00€ *
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(Z)-4-hydroxy Tamoxifen
(Z)-4-hydroxy Tamoxifen

Item number: Cay14854-1

(Z)-4-hydroxy Tamoxifen is an active metabolite of the estrogen receptor (ER) modulator tamoxifen (Cay-13258). It is primarily formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6 and CYP2B6. (Z)-4-hydroxy Tamoxifen (10 nM) decreases progesterone receptor (PR) mRNA expression induced by the estrogen...
Keywords: trans-4-hydroxy Tamoxifen, ICI 79280, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol
Application: Tamoxifen metabolite
CAS 68047-06-3
MW: 387.5 D
From 50.00€ *
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(Z)-4-Hydroxytamoxifen
(Z)-4-Hydroxytamoxifen

Item number: LKT-H9711.5

An active metabolite of (Z)-tamoxifen which exhibits higher potency as estrogen agonist. It binds to estrogen receptors with 8-fold higher affinity than tamoxifen.
Application: Metabolic studies
CAS 68047-06-3
MW: 387,51 D
From 218.00€ *
Review