Description: Cytochalasin H ((16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate) is a potent inhibitor of actin incorporation into filaments. Target: MMP. Smiles:...

The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin H is a potent inhibitor of actin incorporation into filaments. Like cytochalasin D (Cay-11330), it...

White solid. Soluble in DMSO, methanol or acetone. Isolated from Phomopsis sp. Potent mycotoxin. Phytotoxin. Actin polymerization inhibitor. Used in actin polymerization and cytoskeletal reorganization studies. Antibacterial, antifungal, nematocidal and antitumor compound. Apoptosis inducer. Anti-angiogenic agent....

Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins resulting in pronounced morphogenic changes in animals and plants. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumor...