Description: Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo. Target: TRP/TRPV Channel, NOD, AChR, AChE. Smiles: CC(C)=CCOc1c2occc2cc2ccc(=O)oc12. References: Koziol, E., &...

Imperatorin is a furocoumarin present in citrus fruits, which is used in HIV-1 research. It inhibits cyclin D1 expression and stops the cell cycle at G1. Studies suggest that Imperatorin suppresses HIV-1 replication in primary T lymphocytes and transformed cell lines. Imperatorin can also cause apoptosis in human...

White to off-white solid. Soluble in DMSO or dimethyl formamide. Slightly soluble in methanol or water. Insoluble in ethanol. Chemical. CAS: 482-44-0. Formula: C16H14O4. MW: 270.3. Isolated from Opopanax chironium L. Anticancer compound. Apoptosis inducer. Induces DNA fragmentation at the G1/S phase of the cell...

Imperatorin is a furanocoumarin that has been found in A. dahurica and has diverse biological activities, including anticancer, anti-inflammatory, and antioxidant properties. It decreases MCL-1 protein levels and increases mitochondrial membrane depolarization and apoptosis in doxorubicin-resistant HepG2 (R-HepG2)...