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Item number: Cay10009209-1

The phosphatidylinositol 3-kinases (PI3K) family of enzymes is comprised of 15 members that are divided into 3 classes according to their structure, substrate specificity, and mode of regulation. PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with...

Keywords:	3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-phenol
Application:	PI3K inhibitor
CAS	371935-74-9
MW:	348.4 D

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PI103

Item number: SYN-1065-M001

Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PI-103 is an isoform-selective class I PI3K and mTOR inhibitor. It has activity on p110alpha-delta with IC(50) values of 2nM, 3nM, 3nM, 15nM respectively. It is less potent against mTOR and DNA-PK with IC(50) values of 30nM and 23nM respectively. Target: PI3K...

Keywords:	PI-103
Application:	PI3K / DNA-PK / mTOR inhibitor
CAS	371935-74-9
MW:	348,4 D

From 125.00€ *

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