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Item number: TGM-T15582-100mg

Description: inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects. Target: STAT. Smiles: Oc1ccc(cc1)N1C(=O)\C(=C/c2ccc(Cl)cc2)C=C1c1ccccc1. References: Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target...

Application:	STAT3 inhibitor
CAS	328998-53-4
MW:	373.83 D

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inS3-54-A18

Item number: Cay39678-1

inS3-54-A18 is an inhibitor of STAT3. It selectively inhibits the binding of STAT3 to DNA over STAT1 at 25 µM. inS3-54-A18 (20 µM) inhibits STAT3 activity in a reporter assay using MDA-MB-231 breast cancer cells. It induces apoptosis in, and reduces migration and invasion of, A549 non-small cell lung cancer (NSCLC)...

Keywords:	3-[(4-chlorophenyl)methylene]-1,3-dihydro-1-(4-hydroxyphenyl)-5-phenyl-2H-pyrrol-2-one
Application:	STAT3 inhibitor
CAS	328998-53-4
MW:	373.8 D

From 66.00€ *

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