Description: Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system. Target: Others, Endogenous Metabolite. Smiles: CCCCCCCC\C=C/CCCCCCCC(N)=O. References: Mendelson WB, et al. The hypnotic actions of the fatty acid amide, oleamide....

Oleamide is an amide of oleic acid (Cay-90260) and an agonist of cannabinoid 1 (CB1) receptors (Ki = 8.13 µM in a radioligand binding assay). It is selective for CB1 over CB2 receptors, where it inhibits binding of the CB receptor full agonist CP 55,940 by only 42.5% in HEK-293T cells expressing human CB2 receptors...