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AVN-944
Item number: TGM-T1979-100mg
Description: AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. Target: Dehydrogenase. Smiles: CC[C@H](CC#N)OC(=O)N[C@@H](C)c1cccc(NC(=O)Nc2ccc(-c3cnco3)c(OC)c2)c1. References: Zimmermann AG, et al. Prog Nucleic Acid Res Mol Biol. 1998,61:181-209.
| Keywords: | VX-944 |
| Application: | IMPDH inhibitor |
| CAS | 297730-17-7 |
| MW: | 477.51 D |
From 53.00€
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AVN-944
Item number: Cay21284-1
AVN-944 is a selective, noncompetitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH, Ki = 6-10 nM for both human IMPDH isoforms), a rate-limiting enzyme involved in the de novo synthesis of purine nucleotides. Inhibition of IMPDH results in disruption of DNA and RNA synthesis, inhibition of cell...
| Keywords: | N-[(1S)-1-[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]ethyl]-carbamic acid,... |
| Application: | IMPDH inhibitor |
| CAS | 297730-17-7 |
| MW: | 477.5 D |
From 52.00€
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