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Item number: TGM-T2009-100mg

Description: SB-3CT is a potent and specific gelatinase inhibitor for MMP-2 (Ki = 13.9 nM) and MMP-9 (Ki = 600 nM). Target: MMP. Smiles: O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1. References: Brown S, et al. J Am Chem Soc. 2000, 122 (28), 6799-6800.

CAS	292605-14-2
MW:	306.4 D

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SB-3CT

Item number: Cay16337-1

SB-3CT is a selective, mechanism-based inhibitor of the gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9 (Kis = 28 and 400 nM, respectively). First pass metabolism of SB-3CT in vivo produces a monohydroxylated metabolite that has greater inhibitory activity (Kis = 6 and 160 nM for MMP-2 and MMP-9,...

Keywords:	Matrix Metalloproteinase-2/9 Inhibitor IV, MMP-2/MMP-9 Inhibitor IV, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
Application:	MMP-2 / MMP-9 inhibitor
CAS	292605-14-2
MW:	306.4 D

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