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Item number: Cay34542-1

Difelikefalin is a kappa-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the µ-opioid...

Keywords:	CR845, FE 202845, N1-(D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)-4-amino-4-piperidinecarboxylic acid,...
Application:	Kappa-opioid receptor agonist
CAS	2767426-81-1
MW:	679.9 D

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