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TCS 401
Item number: TGM-T7381-100mg
Description: TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 µM. Target: Phosphatase. Smiles: Cl.OC(=O)C(=O)Nc1sc2CNCCc2c1C(O)=O. References: Du Z D , Hu L T , Zhao G Q , et al. Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial...
| Application: | Selective PTP1B inhibitor |
| CAS | 243966-09-8 |
| MW: | 306.72 D |
From 45.00€
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TCS 401
Item number: Cay20393-1
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B, Ki = 0.29 µM). It inhibits the protein phosphatases CD45 D1D2, PTPbeta, PTPepsilon D1, SHP-1, PTPalpha D1, and LAR D1D2 at much higher concentrations (Kis = 59, 560, 1,100, >2,000, >2,000, and >2,000 µM, respectively). Several PTPs have been...
| Keywords: | 2-[(carboxycarbonyl)amino]-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid, monohydrochloride |
| Application: | Selective PTP1B inhibitor |
| CAS | 243966-09-8 |
| MW: | 306.7 D |
From 44.00€
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