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ONO 4817
ONO 4817

Item number: TGM-T21814-1mg

Description: ONO-4817 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (MMPs). It effectively reduces the development of aortic intimal hyperplasia in...
Application: MMP-2 / MMP-9 inhibitor
CAS 223472-31-9
MW: 416.47 D
From 259.00€ *
Review
ONO-4817
ONO-4817

Item number: Cay34058-1

ONO-4817 is an inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 0.5 and 0.8 nM, respectively, for the human enzymes). It is selective for MMP-2 and -9 over MMP-3 and -1 (IC50s = 26 and 2,500 nM, respectively). ONO-4817 (5 µg/ml) decreases bronchoalveolar lavage fluid (BALF) neutrophil infiltration...
Keywords: MMP Inhibitor V, N-[(1S,3S)-1-[(ethoxymethoxy)methyl]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxy-benzamide
Application: MMP-2 / MMP-9 inhibitor
CAS 223472-31-9
MW: 416.5 D
From 142.00€ *
Review