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Item number: Cay26264-1

BDP9066 is an inhibitor of Cdc42-binding kinase alpha (MRCKalpha) and MRCKbeta (Kis = 0.0136 and 0.0233 nM, respectively). It is selective for MRCKalpha and MRCKbeta over Rho-associated kinase 1 (ROCK1) and ROCK2 (Kis = 18.4 and 5.38 nM, respectively) and a panel of 115 additional kinases at 1 µM. BDP9066 has...

Keywords:	(6S)-8-[3-(4-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1,8-diazaspiro[5.5]undecane
Application:	MRCKalpha / MRCKbeta inhibitor
CAS	2226507-04-4
MW:	348.4 D

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BDP9066

Item number: TGM-T14521-100mg

Description: BDP9066 is a potent and selective MRCK inhibitor that inhibits MRCKbeta and MRCKalpha/beta and can be used for the prevention and treatment of skin cancer. Target: ROCK. Smiles: C1CC[C@@]2(CCCN(C2)c2cc[nH]c3ncc(-c4ccncn4)c23)NC1. References: Unbekandt M, et al. Discovery of Potent and Selective MRCK...

CAS	2226507-04-4
MW:	348.44 D

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