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Item number: Cay37673-10

WNK463 is an inhibitor of WNK lysine-deficient protein kinase 1 (WNK1), WNK2, WNK3, and WNK4 (IC50s = 5, 1, 6, and 9 nM, respectively). It is selective for WNK1-4 over a panel of 442 kinases at 10 µM. In vivo, WNK463 (1, 3, and 10 mg/kg) decreases blood pressure, as well as increases urine output and urinary sodium...

Keywords:	N-(1,1-dimethylethyl)-1-[1-[5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]-4-piperidinyl]-1H-imidazole-5-carbox...
Application:	WNK1-4 inhibitor
CAS	2012607-27-9
MW:	463.5 D

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