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Item number: Cay30626-1

ALX 5407 is an inhibitor of glycine transporter 1 (GlyT1, IC50 = 3 nM). It is selective for GlyT1 over GlyT2 (IC50 = >10 µM), as well as over NMDA receptors and the inhibitory glycine receptor at 100 µM. ALX 5407 (10 mg/kg) increases prefrontal cortical levels of glycine in rats. It also reverses MK-801-induced...

Keywords:	(R)-N-(3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl)-N-methylglycine, monohydrochloride
Application:	GlyT1 inhibitor
CAS	200006-08-2
MW:	429.9 D

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