2 products were found matching "193022-04-7"!
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CTS-1027
Item number: TGM-T15015-2mg
Description: CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1. Target: Others. Smiles: ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1. References: Kahraman A, et al. Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver...
| Keywords: | Ro 1130830, RS 130830 |
| Application: | MMP2/9/13 inhibitor |
| CAS | 193022-04-7 |
| MW: | 425.88 D |
95.00€
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CTS-1027
Item number: Cay33219-1
CTS-1027 is an inhibitor of matrix metalloproteinases (MMPs). It is selective for MMP-2, MMP-9, and MMP-13 (Kis= 0.22, 0.55, and 0.52 nM, respectively) over MMP-3 and MMP-1 (Kis= 9.3 and 590 nM, respectively). CTS-1027 (10 mg/kg) reduces hepatocyte apoptosis and bile infarcts and increases survival in a mouse model...
| Keywords: | Ro 113-0830, RS 130830, 4-[[[4-(4-chlorophenoxy)phenyl]sulfonyl]methyl]tetrahydro-N-hydroxy-2H-pyran-4-carboxamide |
| Application: | MMP2/9/13 inhibitor |
| CAS | 193022-04-7 |
| MW: | 425.9 D |
From 100.00€
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