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Item number: Cay38782-1

OT-82 is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor. It inhibits recombinant human and recombinant mouse Nampt in a cell-free assay when used at concentrations ranging from 0.1 to 10 µM. OT-82 is cytotoxic against a panel of 12 hematological cancer cells (IC50s = 1.01-5.64 nM). In vivo, OT-82 (25 and...

Keywords:	3-[2-(4-fluorophenyl)ethynyl]-N-[3-(1H-pyrazol-4-yl)propyl]-4-(4-pyridinyl)-benzamide
Application:	Nampt inhibitor
CAS	1800487-55-1
MW:	424.5 D

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